hepatoprotective activity of mammea africana ethanol stem bark extract

mammea africana sabine (guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. the hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, total cholesterol, alanine aminotransaminase (alt), aspartate aminotransaminase (ast), and alkaline phosphatase activities (alp), antioxidant enzymes: superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), reduced glutathione (gsh) and histopathological study of the liver. the administration of the stembark extract caused significant (p